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Lifestyle changes, including regular exercise, dietary adjustments (such as a low-carbohydrate diet), and maintaining a moderate weight, can sometimes enable individuals with type 2 diabetes to manage their condition without medication
For people with type 2 diabetes, the SURMOUNT-2 trial showed average weight loss of around 12.8%, roughly 57% of the weight loss seen in people without diabetes 3
When to contact your provider: Most first-week side effects are mild and manageable
Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species