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Lee C, Zeng J, Drew BG, et al

Diarrhoea (defined as three or more loose or watery stools per day) is an uncommon side effect of vitamin B12 supplementation , though it is listed as a rare or uncommon adverse reaction in the official product information for both oral cyanocobalamin and injectable hydroxocobalamin preparations

The result is preserved intracellular pools of nicotinamide ( NAD+ salvage substrate) and SAM ( methyl-donor pool)

Immunofixation is the only recommended confirmatory test to establish monoclonality

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This release results in long-term inflammation, tissue issues, articular cartilage injuries, and age-related diseases