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The AUGUSTUS trial (N=4,614) showed that adding aspirin to apixaban in patients with atrial fibrillation and recent acute coronary syndrome increased bleeding events from 7.3% to 10.9% over 6 months (HR 1.89 to 95% CI 1.59 to 2.24) [12]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Wang T.-H., Chou L.-F., Chen C.-C., Yeh C.-T., Liu Y.-T., Chu Y.-D., Lin H.-W., Chen K.-Y., Yu C.-C., Chen C.-Y

Additionally, peptide hormones interact with the gut microbiome to regulate the production of short-chain fatty acids, which are crucial for maintaining a healthy gut environment

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The main antioxidants are superoxide dismutase (SOD), glutathione peroxides, and catalase